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GS-441524;GS441524
R2002141GS-441524 could strongly inhibits feline infectious peritonitis virus (FIPV), with an EC50 of 0.78 μM. Key intermediate for Remdesivir（GS-5734).
Sugammadex sodium (Synonyms: Org25969)
R11425Sugammadex (Org 25969, tradename Bridion) is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia. It is the first selective relaxant binding agent (SRBA).
Encequidar mesylate (HM30181 mesylate; HM30181A mesylate)
R2053528Encequidar mesylate (HM30181 mesylate; HM30181A mesylate) is a competitive and potent P-glycoprotein inhibitor.
Lasmiditan succinate(Synonyms: COL-144 succinate; LY573144 succinate)
R912035Lasmiditan (COL-144) is a high-affinity, highly selective 5-HT1F receptor agonist (Ki=2.1 nM), compared with Ki of 1043 nM and 1357 nM at the 5-HT(1B) and 5-HT(1D) receptors, respectively.
YY-20394;PI3Kδ-IN-2
R910386PI3Kδ-IN-2 is a potent and selective inhibitor of PI3Kδ extracted from patent WO 2015055071 A1, compound 10; has an IC50 of 6.4 nM.
Erdafitinib (Synonyms: JNJ-42756493)
R910183Erdafitinib (JNJ-42756493) is a potent and orally available FGFR family inhibitor; inhibits FGFR1/2/3/4 with IC50s of 1.2, 2.5, 3.0 and 5.7 nM, respectively.
Eliglustat hemitartrate (Synonyms: Genz-112638; Eliglustat tartrate)
R11057Eliglustat tartrate (Genz-112638), a specific inhibitor of glucosylceramide synthase, is under development as an oral substrate reduction therapy for Gaucher disease type 1 (GD1)..gif.gif)
Anamorelin ; RC-1291
R11015Anamorelin(RC1291; ONO-7643) is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia.
Eliglustat (Synonyms: Genz 99067)
R11006Eliglustat (Tartrate) inhibits glucosylceramide synthase(GCS),thus reducing the load of glucosylceramide influx into the lysosome.
Avitinib (AC0010)
R10996Avitinib (AC0010) is a pyrrolopyrimidine-based irreversible EGFR inhibitor that is mutation-selective with IC50 value of 0.18 nM against EGFR L858R/T790M double mutations, nearly 43-fold gre
Tenofovir Alafenamide (GS-7340)
R10583Tenofovir alafenamide (GS-7340) is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor.
GFT505; elafibranor E
R10330Elafibranor is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively.
