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LY2874455; dovitinib
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Details:
Theoretical analysis
CAS NO.:1254473-64-7
Molecular Formula:C21H19N5O2Cl2
Molecular Weight:444.31386
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
LY2874455 is a pan-FGFR inhibitor with IC50 of 2.8 nM, 2.6 nM, 6.4 nM, and 6 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively, and also inhibits VEGFR2 activity with IC50 of 7 nM. Phase 1.
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Quality control data
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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