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PD0332991; PD0332991; Palbociclib
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Details:
Theoretical analysis
CAS NO.:571190-30-2
Molecular Formula:C24H29N7O2
Molecular Weight:447.53
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.
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Quality control data
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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