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Palbociclib hydrochloride;PD 0332991 hydrochloride
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Details:
Theoretical analysis
CAS NO.:827022-32-2
Molecular Formula:C₂₄H₃₀ClN₇O₂
Molecular Weight:483.99
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
Palbociclib (PD-0332991) HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays, respectively. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.
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Quality control data
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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