Spautin 1

CAS NO.:1262888-28-7

Molecular Formula:C₁₅H₁₁F₂N₃

Molecular Weight:271.26

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells with IC50 of 1.03 μM. In contrast, co-treatment with Spautin-1 increased IM-induced inhibition of cell viability with IC50 of 0.45 μM. IC50 value: (1.03 μM, IM for K562 cell; 0.45 μM, Spautin-1 and IM for K562 cell).

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Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

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