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H3B-6527
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Details:
Theoretical analysis
CAS NO.:1702259-66-2
Molecular Formula:C₂₉H₃₄Cl₂N₈O₄
Molecular Weight:629.54
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
H3B-6527 is an orally active, highly selective and covalent FGFR4 inhibitor with an IC50 of <1.2 nM. H3B-6527 has at least 250-fold selectivity over FGFR1-3 with IC50s of 320, 1290 and 1060 nM respectively. H3B-6527 has potent anti-cancer activity.
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Quality control data
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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