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VcMMAE (Synonyms: mc-vc-PAB-MMAE)

Catalog No.: R12024
CAS No.: 646502-53-6
Formula: C68H105N11O15
Weight: 1316.62601828575
Details:
Theoretical analysis

CAS NO.:646502-53-6

Molecular Formula:C68H105N11O15

Molecular Weight:1316.62601828575

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
VcMMAE (mc-vc-PAB-MMAE) is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc). 
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Quality control data

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

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