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ZK824859

Catalog No.: R910291
CAS No.: 2254001-81-3
Formula: C22H20F2N2O4
Weight: 414.40200
Details:
Theoretical analysis

CAS NO.:2254001-81-3

Molecular Formula:C22H20F2N2O4

Molecular Weight:414.40200

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
ZK824859 (ZK-824859) is a potent, selective urokinase plasminogen activator (uPA) inhibitor with IC50 of 79 nM (human uPA), displays little to no inhibitory activity against tPA and Plasmin (IC50>1 uM); ZK 824859 is 5 fold less potent and has lost selectivity in mouse: uPA IC50=410 nM; tPA IC50=910 nM; plasmin IC50=1600 nM; demonstrates efficacy in either acute or chronic mouse EAE models.
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Packing: 10mg/50mg/100mg/500mg/1g and we provide a variety of packaging.

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Quality control data

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

Product will be shipped with supporting analytical data.

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