Niraparib Tosylate Monohydrate

CAS NO.:1613220-15-7

Molecular Formula:C₂₆H₂₈N₄O₄S

Molecular Weight:500.59000

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Niraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC50 of 3.8 and 2.1 nM, respectively. Niraparib tosylate (MK-4827 tosylate) leads to inhibition of repair of DNA damage and shows anti-tumor activity.

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