Motesanib Diphosphate (AMG-706) VM-2005

CAS NO.:857876-30-3

Molecular Formula:C₂₂H₂₉N₅O₉P₂

Molecular Weight:569.441286802292

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Motesanib Diphosphate (AMG 706 Diphosphate) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50s of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is approximately 10-fold more selective for VEGFR than PDGFR and Ret. 

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