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IQ-1S free acid

Catalog No.: R2030136
CAS No.: 23146-22-7
Formula: C15H9N3O
Weight: 247.251462697983
Details:
Theoretical analysis

CAS NO.:23146-22-7

Molecular Formula:C15H9N3O

Molecular Weight:247.251462697983

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
IQ-1S free acid is a prospective inhibitor of NF-κB/activating protein 1 (AP-1) activity with an IC50 of 2.3±0.41 μM. IQ-1S free acid has binding affinity (Kd values) in the nanomolar range for all three JNKs with Kds of 100 nM, 240 nM, and 360 nM for JNK3, JNK1, and JNK2, respectively. 
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Quality control data

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

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