Allitinib (AST-1306; ALS 1306)

CAS NO.:897383-62-9

Molecular Formula:C₂₄H₁₈ClFN₄O₂

Molecular Weight:448.88

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Allitinib (AST-1306) is an orally active and irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. Allitinib also inhibits ErbB4 with an IC50 of 0.8 nM. Allitinib is an anilino-quinazoline compound and has anti-cancer activity.

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