Filanesib hydrochloride(ARRY-520)

CAS NO.:1385020-40-5

Molecular Formula:C₂₀H₂₃ClF₂N₄O₂S

Molecular Weight:456.94

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Filanesib (ARRY-520) hydrochloride is a selective and noncompetitive kinesin spindle protein (KSP) inhibitor, with an IC50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. It has potent anti-proliferative activity.

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