N'-(4-(二乙基氨基)-2-羟基亚苄基)异烟酰肼

CAS NO.:140405-36-3

Molecular Formula:C₁₇H₂₀N₄O₂

Molecular Weight:312.37

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

RSVA405 is a potent, orally active activator of AMPK, with an EC50 of 1 μM. RSVA405 facilitates CaMKKβ-dependent activation of AMPK, inhibits mTOR, and promotes autophagy to increase Aβ degradation. RSVA405 has anti-inflammatory effects through the inhibition of STAT3 function. RSVA405 can also be used for the research of obesity.

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