R10030 |
MLN4924 |
MLN4924 is a potent and selective small molecule NEDD8-activating enzyme (NAE) i
|
R10031 |
BIIB-024; MLN2480 |
MLN2480(BIIB-024) is an oral, selective pan-Raf kinase inhibitor in chinical tri
|
R10032 |
SLx-2119 (KD-025) |
SLx-2119(KD-025) is a small molecule and selective inhibitor of ROCK2 with IC50
|
R10033 |
MLN8237 |
Alisertib (MLN8237) is a selective Aurora A inhibitor with IC50 of 1.2 nM in a c
|
R10034 |
MK8745 |
MK-8745 is a potent and selective Aurora A inhibitor with IC50 of 0.6 nM, more t
|
R10035 |
MDL28170 |
MDL 28170 is a cell permeable selective inhibitor of Calpain 1, a Ca2+-dependent
|
R10036 |
XL880; Foretinib; GSK136308 |
Foretinib (GSK1363089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly
|
R10037 |
ANA12 |
ANA-12 is a selective TrkB antagonist with Kd of 10 nM and 12 μM for the high an
|
R10038 |
CX-4945 |
CX-4945 (Silmitasertib) is a potent and selective inhibitor of CK2 (casein kinas
|
R10040 |
IP-145; Duvelisib; INK1197 |
Duvelisib (IPI-145, INK1197) is a novel and selective PI3K δ/γ inhibitor with Ki
|
R10041 |
Vesnarinone (OPC-8212) |
Vesnarinone is a quinolinone derivative, and its pharmacodynamic effects include
|
R10042 |
CO1686; Rociletinib |
Rociletinib (CO-1686, AVL-301) is an irreversible, mutant-selective EGFR inhibit
|
R10044 |
WZ4003 |
WZ4003 is a highly specific NUAK kinase inhibitor with IC50 of 20 nM and 100 nM
|
R10045 |
Fluoroclebopride |
|
R10046 |
TORIN1 |
Torin 1 is a potent inhibitor of mTORC1/2 with IC50 of 2 nM/10 nM in cell-free a
|
R10047 |
Vortioxetine |
Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5
|
R10048 |
Temsavir; BMS-626529 |
BMS-626529 is a novel small-molecule attachment inhibitor that targets HIV-1 gp1
|
R10049 |
TP-808;TP808 |
TP808 is an intermediate that influences the synthesis of diverse tetracycline a
|
R10054 |
TAE684 |
TAE684 (NVP-TAE684) is a potent and selective ALK inhibitor with IC50 of 3 nM in
|
R10056 |
Tubastatin-A |
Tubastatin A is a potent and selective HDAC6 inhibitor withIC50 o
|
R10058 |
Masitinib |
Masitinib is a novel inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540
|
R10060 |
Nadifloxacin; Acuatim; Nadixa; OPC7251 |
Nadifloxacin is a topical fluoroquinolone antibiotic for the treatment of acne v
|
R10061 |
Nexavar; Bay 43-9006; Sorafenib |
Sorafenib Tosylate is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with I
|
R10062 |
SAR131675 |
SAR131675 is a VEGFR3 inhibitor with IC50/Ki of 23 nM/12 nM in cell-free assays,
|
R10064 |
Brivanib; BMS540215 |
Brivanib is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, mode
|