R10162 |
Apremilast; CC10004 |
Apremilast (CC-10004) is a potent and orally active PDE4 and TNF-α inhibitor wit
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R10164 |
Avibactam sodium; NXL-104 |
Avibactam sodium(NXL-104) is a non-β-lactam β-lactamase inhibitor antibiotic.
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R10167 |
PI103 Free base |
PI-103 is a multi-targeted PI3K inhibitor for p110α/β/δ/γ with IC50 of 2 nM/3 nM
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R10168 |
YM201636 |
YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p11
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R10174 |
PF429242 |
PF 429242 is a reversible, competitive inhibitor of sterol regulatory element-bi
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R10177 |
GSK364735 |
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R10179 |
4SC201 |
Resminostat dose-dependently and selectively inhibits HDAC1/3/6 with IC50 of 42.
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R10180 |
Torin2 |
Torin 2 is a potent and selective mTOR inhibitor with IC50 of 0.25 nM in p53−/−
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R10181 |
AP24534; Ponatinib |
Ponatinib (AP24534) is a novel, potent multi-target inhibitor of Abl, PDGFRα, VE
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R10184 |
GW9508 |
GW9508 is a potent and selective agonist for FFA1 (GPR40) with pEC50 of 7.32, 10
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R10185 |
Otenabant Hydrochloride (CP 945598 Hydrochloride) |
Otenabant (CP-945598) HCl is a potent and selective cannabinoid receptor CB1 ant
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R10186 |
CP945598 free base |
Otenabant (CP945598) is a recently discovered selective, high affinity, competit
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R10188 |
ciproxifan; FUB359 |
Ciproxifan is a highly potent and selective histamin H3-receptor antagonist with
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R10189 |
AT7519 HCl |
AT7519 HCl is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210
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R10190 |
BIX02188 |
BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK
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R10191 |
Tacedinaline (N-acetyldinaline; CI-994; Goe-5549) |
CI994 (Tacedinaline) is an anti-cancer drug which inhibits HDAC1 with IC50 of 0.
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R10192 |
ZM323881HCl |
ZM 323881 is a potent and selective VEGFR2 inhibitor with IC50 of <2 nM, almo
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R10193 |
ZM 306416 (Synonyms: CB 676475) |
ZM 306416 is a VEGFR (Flt and KDR) inhibitor for VEGFR1 with IC50 of 0.33 μM, bu
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R10194 |
OC000459 |
OC000459 is a potent and selective D prostanoid receptor 2 (DP2) antagonist with
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R10195 |
Enasidenib; AG221 |
Enasidenib is a oral potent, selective, reversible inhibitor of mutant IDH2.
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R10197 |
AZ-33 |
AZ-33:
2-(4-(4-(3-(2-methylbenzo[d]thiazol-6-ylamino)-3-oxopropylamino)-4-oxobut
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R10201 |
IP145; Duvelisib; Impurity comparison |
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R10202 |
AZD4547 |
AZD4547 is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2
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R10204 |
PF562271 |
PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK wi
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R10209 |
indisulam; E7070 |
Indisulam (E7070) is a carbonic anhydrase inhbitor, is also a novel synthetic su
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