R10008 |
Rucaparib phosphate; AG014699; PF01367388 |
Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for
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R10010 |
Rucaparib; AG-014699; PF-01367388 |
Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for
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R10015 |
MN-64 |
MN-64 is a inhibitor of tankyrases, showed 6 nM potency against tankyrase 1, iso
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R10026 |
Ruxolitinib (INCB018424) |
CAS NO.:941678-49-5Product Name:β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl
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R10033 |
MLN8237 |
Alisertib (MLN8237) is a selective Aurora A inhibitor with IC50 of 1.2 nM in a c
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R10034 |
MK8745 |
MK-8745 is a potent and selective Aurora A inhibitor with IC50 of 0.6 nM, more t
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R10056 |
Tubastatin-A |
Tubastatin A is a potent and selective HDAC6 inhibitor withIC50 o
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R10071 |
SRT1720 HCl |
SRT1720 is a selective SIRT1 activator with EC50 of 0.16 μM in a cell-free assay
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R10096 |
IOX2 |
IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21
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R10104 |
PF03814735 |
PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50o
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R10108 |
Olaparib (Synonyms: AZD2281; KU0059436) |
Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5
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R10130 |
VX-680 (Tozasertib, MK-0457) |
VX-680 (Tozasertib, MK-0457) is a pan-Aurora inhibitor, mostly against Aurora A
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R10131 |
Momelotinib (CYT387) |
Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 1
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R10153 |
Roxadustat (FG-4592) |
Roxadustat (FG-4592) is an HIF α prolyl hydroxylase inhibitor in a cell-free ass
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R10179 |
4SC201 |
Resminostat dose-dependently and selectively inhibits HDAC1/3/6 with IC50 of 42.
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R10191 |
Tacedinaline (N-acetyldinaline; CI-994; Goe-5549) |
CI994 (Tacedinaline) is an anti-cancer drug which inhibits HDAC1 with IC50 of 0.
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R10213 |
SGI1776 |
SGI-1776 free base is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 n
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R10224 |
Sirtinol |
Sirtinol is a specific SIRT1 and SIRT2 inhibitor with IC50 of 131 μM and 38 μM i
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R10236 |
Talazoparib (BMN 673) |
Talazoparib (BMN 673) is a novel PARP inhibitor with IC50 of 0.58 nM in a cell-f
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R10239 |
Tubastain A |
Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a c
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R10247 |
Veliparib dihydrochloride; ABT-888 dihydrochloride |
Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM a
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R10269 |
FG-2216 (Synonyms: IOX3; YM311) |
FG-2216 is a potent HIF-prolyl hydroxylase inhibitor with IC50 of 3.9 uM for PDH
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R10270 |
GSK2801 |
GSK2801 is a selective bromodomains BAZ2A/B inhibitor with KD of 257 nM and 136
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R10273 |
G007-LK |
G007-LK is a potent and selective inhibitor of TNKS1 and TNKS2, with IC50s of 46
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R10313 |
KU0059436; AZD2281; OlaparibIntermediate |
Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5
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