R10766 |
SC-202671 |
JNK inhibitor IX is a selective and potent JNK inhibitor with pIC50 of 6.5 and 6
|
R10777 |
bml-210 |
BML-210 is the novel HDAC inhibitor, and its mechanism of action has not been ch
|
R10778 |
Pimelic diphenylamide 106; TC-H106 |
Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I HDAC (HD
|
R10779 |
UF010 |
UF010 is a potent and selective HADC inhibitor with IC50 ~0.06 μM, 0.1 μM, 0.5 μ
|
R10780 |
KC7F2 |
KC7F2 is a potent HIF-1 pathway inhibitor and that its potential as a cancer the
|
R10781 |
WDR50103 |
WDR5-0103 is a potent and selective WD repeat-containing protein 5 (WDR5) antago
|
R10793 |
(-)-JQ1 |
The bromodomain and extra terminal domain (BET) family of proteins, including BR
|
R10803 |
PX478 dihydrochloride |
PX-478 2HCl is an orally active, and selective hypoxia-inducible factor-1α (HIF-
|
R10835 |
Birabresib (Synonyms: OTX-015; MK-8628) |
OTX015 is a potent BET bromodomain inhibitor with EC50 ranging from 10 to 19 nM
|
R10886 |
Domatinostat (4SC-202 free base) |
Domatinostat (4SC-202 free base) is a selective class I HDAC inhibitor with IC50
|
R10845 |
Veliparib;ABT-888 |
Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM a
|
R10903 |
CEP-33779 |
CEP33779 is a selective JAK2 inhibitor with IC50 of 1.8 nM, >40- and >800-
|
R10915 |
GSK3235025;EPZ-015666;GSK-3235025 |
EPZ015666 is a potent, selective and orally bioavailable PRMT5 inhibitor with Ki
|
R10925 |
ML324 |
ML324 is a selective inhibitor of jumonji histone demethylase (JMJD2) with IC50
|
R10929 |
UNC1215 |
UNC1215 is a potent and selective MBT (malignant brain tumor) antagonist, which
|
R10978 |
BIX-01294 |
BIX01294 is an inhibitor of G9a histone methyltransferase with IC50 of 2.7 μM in
|
R10981 |
UNC0379 |
UNC0379 is a selective, substrate competitive inhibitor of N-lysine methyltransf
|
R10989 |
SGC707 |
SGC707 is a potent, selective and cell-active allosteric inhibitor of protein ar
|
R10990 |
SP2509 |
SP2509 is a selective histone demethylase LSD1 inhibitor with IC50 of 13 nM, sho
|
R11000 |
Baricitinib phosphate;LY3009104 phosphate; INCB028050 phosphate |
Baricitinib (LY3009104, INCB028050) is a selective JAK1 and JAK2 inhibitor with
|
R11001 |
LY2784544 |
Gandotinib (LY2784544) is a potent JAK2 inhibitor withIC50 of 3 n
|
R11453 |
JNJ26854165;Quisinostat 2HCl |
Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with
|
R11471 |
GLPG0634 analog |
GLPG0634 analogue is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 n
|
R11501 |
Panobinostat (LBH589; NVP-LBH589) |
Panobinostat (LBH589) is a novel broad-spectrum HDAC inhibitor with IC50 of 5 nM
|
R11530 |
RG2833 (RGFP109) |
RG2833 (RGFP109) is a brain-penetrant HDAC inhibitor with IC50 of 60 nM and 50 n
|