R10003 |
Infigratinib (Synonyms: BGJ-398; NVP-BGJ398) |
BGJ398 (NVP-BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with
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R10006 |
Allitinib tosylate (Synonyms: AST-1306 (TsOH))/897383-62-9 Free base |
AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM
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R10036 |
XL880; Foretinib; GSK136308 |
Foretinib (GSK1363089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly
|
R10037 |
ANA12 |
ANA-12 is a selective TrkB antagonist with Kd of 10 nM and 12 μM for the high an
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R10042 |
CO1686; Rociletinib |
Rociletinib (CO-1686, AVL-301) is an irreversible, mutant-selective EGFR inhibit
|
R10054 |
TAE684 |
TAE684 (NVP-TAE684) is a potent and selective ALK inhibitor with IC50 of 3 nM in
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R10058 |
Masitinib |
Masitinib is a novel inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540
|
R10061 |
Nexavar; Bay 43-9006; Sorafenib |
Sorafenib Tosylate is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with I
|
R10062 |
SAR131675 |
SAR131675 is a VEGFR3 inhibitor with IC50/Ki of 23 nM/12 nM in cell-free assays,
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R10064 |
Brivanib; BMS540215 |
Brivanib is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, mode
|
R10076 |
Crizotinib (PF-02341066) |
Crizotinib (PF-02341066) is a potent inhibitor of c-Met and ALK with IC50 of 11
|
R10077 |
AMG208 |
AMG 208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.
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R10078 |
EMD1214063 |
Tepotinib (EMD 1214063) is a potent and selective c-Met inhibitor with IC50 of 4
|
R10087 |
AZD9291 |
Osimertinib (AZD9291) is an oral, irreversible, and mutant-selective EGFR inhibi
|
R10118 |
Regorafenib; BAY73-4506; BAY734506 |
Regorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3
|
R10126 |
WZ4002 |
WZ4002 is a novel, mutant-selective EGFR inhibitor for EGFR(L858R)/(T790M) with
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R10127 |
Linifanib (Synonyms: ABT-869; AL-39324) |
Linifanib (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for
|
R10138 |
Tivozanib;AV-951; KRN951 |
Tivozanib (AV-951) is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with
|
R10143 |
Cabozantinib (XL184; BMS-907351) |
Cabozantinib (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0.035
|
R10150 |
Ceritinib; LKD378 |
Ceritinib (LDK378) is potent inhibitor against ALK with IC50 of 0.2 nM in cell-f
|
R10151 |
E7080; Lenvatinib |
Lenvatinib (E7080) is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Fl
|
R10152 |
Neratinib; HKI272 |
Neratinib (HKI-272) is a highly selective HER2 and EGFR inhibitor with IC50 of 5
|
R10156 |
Nintedanib; BIBF1120 |
Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3,
|
R10192 |
ZM323881HCl |
ZM 323881 is a potent and selective VEGFR2 inhibitor with IC50 of <2 nM, almo
|
R10193 |
ZM 306416 (Synonyms: CB 676475) |
ZM 306416 is a VEGFR (Flt and KDR) inhibitor for VEGFR1 with IC50 of 0.33 μM, bu
|