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Cat.No. | Product name | Product Description |
R10005 | AT406 (SM-406, ARRY-334543) | AT-406 is an orally bioavailable inhibitor of IAP family of proteins with potent |
R10094 | RITA (NSC652287) | RITA (NSC 652287) induces both DNA-protein and DNA-DNA cross-links with no detec |
R10095 | Tenovin1 | Tenovin-1 protects against MDM2-mediated p53 degradation, which involves ubiquit |
R10119 | PAC-1 (Synonyms: Procaspase activating compound 1) | PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM and the first smal |
R10333 | Navitoclax (Synonyms: ABT-263) | ABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of |
R10425 | Spautin 1 | Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells |
R10511 | Lenalidomide; CC5013 | Lenalidomide (CC-5013) is a TNF-α secretion inhibitor with IC50 of 13 nM in PBMC |
R10553 | Venetoclax; ABT199 | Venetoclax (ABT-199, GDC-0199) is a Bcl-2-selective inhibitor with Ki of <0.0 |
R10628 | MDK83190 | Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and |
R10763 | Kevetrin hydrochloride; NSC525990 | Kevetrin hydrochloride is a small molecule and activator of the tumor suppressor |
R10786 | FMK | FMK is a RSK2 kinase inhibitor. |
R10799 | LCL161 Enantiomer | LCL161 is an orally bioavailable second mitochondrial-derived activator of caspa |
R10802 | Nutlin-3 | MDM2 antagonist nutlin-3 is a potent inducer of apoptosis. |
R10827 | RG7112 (Synonyms: RO5045337) | RG7112 is the first clinical small-molecule MDM2 inhibitor designed to occupy th |
R11535 | NSC59984 | NSC59984 is a p53 pathway activator via induction of mutant p53 protein degradat |
R11566 | Tasisulam;LY573636 | Tasisulam is an antitumor agent and an apoptosis inducer via the intrinsic pathw |
R11638 | Emricasan, (IDN-6556; PF-03491390) | Emricasan is a potent irreversible pan-caspase inhibitor. |