R10032 |
SLx-2119 (KD-025) |
SLx-2119(KD-025) is a small molecule and selective inhibitor of ROCK2 with IC50
|
R10046 |
TORIN1 |
Torin 1 is a potent inhibitor of mTORC1/2 with IC50 of 2 nM/10 nM in cell-free a
|
R10262 |
LY294002 |
LY294002 is the first synthetic molecule known to inhibit PI3Kα/δ/β with IC50 of
|
R10378 |
Erlotinib Hydrochloride (CP-358774 Hydrochloride; NSC 718781 Hydrochloride; OSI-774 Hydrochloride) |
Erlotinib HCl (OSI-744) is an EGFR inhibitor with IC50 of 2 nM in cell-free assa
|
R10430 |
Rapamycin; Sirolimus |
Rapamycin (Sirolimus) is a specific mTOR inhibitor with IC50 of ~0.1 nM HEK293 c
|
R10450 |
Erlotinib; NSC718781; OSI744; R1415 |
Erlotinib is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive f
|
R10550 |
Vorinostat |
Vorinostat (suberoylanilide hydroxamic acid, SAHA) is an HDAC inhibitor with IC5
|
R10599 |
3-Methyladenine; 3-MA |
3-Methyladenine (3-MA) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC
|
R10706 |
MHY1485 |
MHY1485 is a potent, and cell-permeable mTOR activator, and also potently inhibi
|
R10716 |
CZC54252;CZC-54252 |
CZC-54252 is a potent inhibitor of LRRK2 with IC50s of 1.28 nM and 1.85 nM for w
|
R10726 |
PF-06447475 |
PF-06447475 is a highly potent, selective and brain penetrant LRRK2 inhibitor wi
|
R11628 |
GSK2578215A |
GSK2578215A is a potent and selective LRRK2 kinase inhibitor with IC50 of 8.9 nM
|